William Blair slashes price target on uniQure N.V [QURE] – find out why.

Brandon Evans

uniQure N.V [NASDAQ: QURE] surged by $4.69 during the normal trading session on Tuesday and reaching a high of $31.43 during the day while it closed the day at $30.84.

uniQure N.V stock has also gained 1.31% of its value over the past 7 days. However, QURE stock has inclined by 111.23% in the 3 months of the year. Over the past six months meanwhile, it has gained 140.75% and gained 315.07% year-on date.

The market cap for QURE stock reached $1.90 billion, with 62.17 million shares outstanding and 54.63 million shares in the current float. Compared to the average trading volume of 4.08M shares, QURE reached a trading volume of 6092761 in the most recent trading day, which is why market watchdogs consider the stock to be active.

Here’s what leading stock market gurus have to say about uniQure N.V [QURE]:

Based on careful and fact-backed analyses by Wall Street experts, the current consensus on the target price for QURE shares is $55.91 per share. Analysis on target price and performance of stocks is usually carefully studied by market experts, and the current Wall Street consensus on QURE stock is a recommendation set at 1.46. This rating represents a strong Buy recommendation, on the scale from 1 to 5, where 5 would mean strong sell, 4 represents Sell, 3 is Hold, and 2 indicates Buy.

William Blair have made an estimate for uniQure N.V shares, keeping their opinion on the stock as Mkt Perform, with their previous recommendation back on November 04, 2025. The new note on the price target was released on August 14, 2025, representing the official price target for uniQure N.V stock. Previously, the target price had yet another raise to $38, while Chardan Capital Markets analysts kept a Buy rating on QURE stock.

The Price to Book ratio for the last quarter was 8.38, with the Price to Cash per share for the same quarter was set at 11.27.

QURE stock trade performance evaluation

uniQure N.V [QURE] gain into the green zone at the end of the last week, gaining into a positive trend and gaining by 1.31. With this latest performance, QURE shares dropped by -50.27% in over the last four-week period, additionally plugging by 140.75% over the last 6 months – not to mention a rise of 74.63% in the past year of trading.

Overbought and oversold stocks can be easily traced with the Relative Strength Index (RSI), where an RSI result of over 70 would be overbought, and any rate below 30 would indicate oversold conditions. An RSI rate of 50 would represent a neutral market momentum. The current RSI for QURE stock in for the last two-week period is set at 35.75, with the RSI for the last a single of trading hit 6.47, and the three-weeks RSI is set at 5.56 for uniQure N.V [QURE]. The present Moving Average for the last 50 days of trading for this stock 42.55, while it was recorded at 27.67 for the last single week of trading, and 21.03 for the last 200 days.

uniQure N.V [QURE]: An insightful look at the core fundamentals

Operating Margin for any stock indicates how profitable investing would be, and uniQure N.V [QURE] shares currently have an operating margin of -1225.66% and a Gross Margin at -14.37%. uniQure N.V’s Net Margin is presently recorded at -1492.90%.

uniQure N.V (QURE) Capital Structure & Debt Analysis

According to recent financial data for uniQure N.V. ( QURE), the Return on Equity (ROE) stands at -165.27%, highlighting a negative impact on investor capital. The Return on Assets (ROA) is -30.65%, reflecting the company’s efficiency in generating profits from its assets. Additionally, uniQure N.V’s Return on Invested Capital (ROIC) is -31.08%, showcasing its effectiveness in deploying capital for earnings.

uniQure N.V (QURE) Efficiency & Liquidity Metrics

Based on uniQure N.V’s (QURE) latest financial statements, the Debt-to-Equity Ratio is 2.32%, indicating its reliance on debt financing relative to shareholder equity.

uniQure N.V (QURE) Efficiency & Liquidity Metrics

From an operational efficiency perspective, uniQure N.V. (QURE) effectively leverages its workforce, generating an average of -$1125119.62 per employee. The company’s liquidity position is robust, with a Current Ratio of 7.12% and a Quick Ratio of 7.12%, indicating strong ability to cover short-term liabilities.

Earnings per share (EPS) analysis for uniQure N.V [QURE] stock

With the latest financial reports released by the company, uniQure N.V posted -1.44/share EPS, while the average EPS was predicted by analysts to be reported at -0.52/share. When compared, the two values demonstrate that the company fail the estimates by a Surprise Factor of -0.92. The progress of the company may be observed through the prism of EPS growth rate, while Wall Street analysts are focusing on predicting the 5-year EPS growth rate for QURE. When it comes to the mentioned value, analysts are expecting to see the 5-year EPS growth rate for uniQure N.V go to 30.60%.

uniQure N.V [QURE]: Institutional Ownership

There are presently around $88.89%, or 93.91%% of QURE stock, in the hands of institutional investors. The top three institutional holders of QURE stocks are: VESTAL POINT CAPITAL, LP with ownership of 4.75 million shares, which is approximately 9.7692%. NANTAHALA CAPITAL MANAGEMENT, LLC, holding 2.65 million shares of the stock with an approximate value of $$11.87 million in QURE stocks shares; and NANTAHALA CAPITAL MANAGEMENT, LLC, currently with $$8.63 million in QURE stock with ownership which is approximately 3.9606%.

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