Karyopharm Therapeutics Inc. [KPTI] stock Initiated by Piper Sandler analyst, price target now $8

Karyopharm Therapeutics Inc. [NASDAQ: KPTI] slipped around -0.44 points on Tuesday, while shares priced at $4.15 at the close of the session, down -9.59%. The company report on April 18, 2023 that Karyopharm Announces Presentation of Updated Phase 1 Selinexor Data in Patients with Treatment-Naïve Myelofibrosis at AACR 2023.

–  At Week 24, 60mg of Selinexor in Combination with Ruxolitinib Achieved: 92% SVR35 and 78% TSS50 in Efficacy Evaluable Population, 79% SVR35 and 58% TSS50 in Intent to Treat Population –.

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– Rapid, Deep, Sustained Spleen Response Across all Subgroups, Robust Symptom Improvement with a Generally Tolerable and Manageable Side Effect Profile; 60mg Selinexor is the Recommended Dose in Combination with Ruxolitinib –.

Karyopharm Therapeutics Inc. stock is now 22.06% up from its year-to-date (YTD) trading value. KPTI Stock saw the intraday high of $4.7054 and lowest of $3.85 per share. The company’s 52-week high price is 7.81, which means current price is +53.70% above from all time high which was touched on 04/17/23.

Compared to the average trading volume of 2.33M shares, KPTI reached a trading volume of 4509838 in the most recent trading day, which is why market watchdogs consider the stock to be active.

What do top market gurus say about Karyopharm Therapeutics Inc. [KPTI]?

Based on careful and fact-backed analyses by Wall Street experts, the current consensus on the target price for KPTI shares is $8.89 per share. Analysis on target price and performance of stocks is usually carefully studied by market experts, and the current Wall Street consensus on KPTI stock is a recommendation set at 2.20. This rating represents a strong Buy recommendation, on the scale from 1 to 5, where 5 would mean strong sell, 4 represents Sell, 3 is Hold, and 2 indicates Buy.

Piper Sandler have made an estimate for Karyopharm Therapeutics Inc. shares, keeping their opinion on the stock as Overweight, with their previous recommendation back on January 19, 2023. While these analysts kept the previous recommendation, RBC Capital Mkts dropped their target price from $7 to $10. The new note on the price target was released on November 04, 2022, representing the official price target for Karyopharm Therapeutics Inc. stock. Previously, the target price had yet another raise to $8, while JP Morgan analysts kept a Neutral rating on KPTI stock. On November 19, 2021, analysts decreased their price target for KPTI shares from 27 to 10.

The Average True Range (ATR) for Karyopharm Therapeutics Inc. is set at 0.39, with the Price to Sales ratio for KPTI stock in the period of the last 12 months amounting to 3.01.

How has KPTI stock performed recently?

Karyopharm Therapeutics Inc. [KPTI] fell into the red zone at the end of the last week, falling into a negative trend and dropping by -0.24. With this latest performance, KPTI shares gained by 22.06% in over the last four-week period, additionally sinking by -13.36% over the last 6 months – not to mention a drop of -46.79% in the past year of trading.

Overbought and oversold stocks can be easily traced with the Relative Strength Index (RSI), where an RSI result of over 70 would be overbought, and any rate below 30 would indicate oversold conditions. An RSI rate of 50 would represent a neutral market momentum. The current RSI for KPTI stock in for the last two-week period is set at 56.31, with the RSI for the last a single of trading hit 54.79, and the three-weeks RSI is set at 56.29 for Karyopharm Therapeutics Inc. [KPTI]. The present Moving Average for the last 50 days of trading for this stock 3.50, while it was recorded at 4.24 for the last single week of trading, and 4.30 for the last 200 days.

Karyopharm Therapeutics Inc. [KPTI]: Deeper insight into the fundamentals

Operating Margin for any stock indicates how profitable investing would be, and Karyopharm Therapeutics Inc. [KPTI] shares currently have an operating margin of -90.53 and a Gross Margin at +96.29. Karyopharm Therapeutics Inc.’s Net Margin is presently recorded at -105.23.

Return on Total Capital for KPTI is now -108.01, given the latest momentum, and Return on Invested Capital for the company is -128.07. Additionally, KPTI Total Debt to Total Capital is recorded at 110.26, with Total Debt to Total Assets ending up at 50.00.

Reflecting on the efficiency of the workforce at the company, Karyopharm Therapeutics Inc. [KPTI] managed to generate an average of -$429,327 per employee. Receivables Turnover for the company is 4.51 with a Total Asset Turnover recorded at a value of 0.47.Karyopharm Therapeutics Inc.’s liquidity data is similarly interesting compelling, with a Quick Ratio of 5.20 and a Current Ratio set at 5.30.

Insider trade positions for Karyopharm Therapeutics Inc. [KPTI]

There are presently around $454 million, or 88.20% of KPTI stock, in the hands of institutional investors. The top three institutional holders of KPTI stocks are: AVIDITY PARTNERS MANAGEMENT LP with ownership of 9,633,911, which is approximately New of the company’s market cap and around 1.40% of the total institutional ownership; BLACKROCK INC., holding 8,508,237 shares of the stock with an approximate value of $39.05 million in KPTI stocks shares; and RUBRIC CAPITAL MANAGEMENT LP, currently with $38.07 million in KPTI stock with ownership of nearly 107.879% of the company’s market capitalization.

Positions in Karyopharm Therapeutics Inc. stocks held by institutional investors increased at the end of Thursday and at the time of the Thursday reporting period, where 93 institutional holders increased their position in Karyopharm Therapeutics Inc. [NASDAQ:KPTI] by around 40,212,078 shares. Additionally, 62 investors decreased positions by around 7,956,955 shares, while 20 investors held positions by with 50,646,479 shares. The mentioned changes placed institutional holdings at 98,815,512 shares, according to the latest SEC report filing. KPTI stock had 32 new institutional investments in for a total of 22,379,732 shares, while 22 institutional investors sold positions of 3,227,344 shares during the same period.


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