Merck & Co. Inc. [NYSE: MRK] price plunged by -0.04 percent to reach at -$0.03. The company report on March 8, 2021 that Merck Presents Results from Phase 1 Trial Evaluating Investigational Islatravir Subdermal Implant for the Prevention of HIV-1 Infection at CROI 2021.
Company to Proceed with Phase 2 Development Program for Islatravir Subdermal Implant.
Merck (NYSE: MRK), known as MSD outside the United States and Canada, announced results from a Phase 1 study evaluating the safety, tolerability and pharmacokinetics (PK) of the company’s investigational subdermal drug-eluting implant with potential for extended administration of islatravir for pre-exposure prophylaxis (PrEP) of HIV-1 infection. Islatravir is an investigational nucleoside reverse transcriptase translocation inhibitor (NRTTI) currently being evaluated across a variety of doses, formulations and frequencies for both the treatment of HIV-1 infection in combination with other antiretroviral agents and for the prevention of HIV-1 infection as a single agent. Study results, presented as a late-breaking oral presentation [Presentation 88] at the 2021 Conference on Retroviruses and Opportunistic Infections (CROI 2021), demonstrate that the implant achieved active drug concentrations above the pre-specified PK threshold at 12 weeks across the three doses of islatravir studied (48 mg, 52 mg and 56 mg), and is projected to provide drug concentrations likely above threshold for one year at the 56 mg dose. Based on these findings, Merck plans to initiate a Phase 2 trial to further explore the potential of a subdermal implant containing islatravir as a long-acting option for PrEP for up to 12 months.
A sum of 13522521 shares traded at recent session while its average daily volume was at 10.54M shares. Merck & Co. Inc. shares reached a high of $75.46 and dropped to a low of $74.13 until finishing in the latest session at $74.14.
The one-year MRK stock forecast points to a potential upside of 23.04. The average equity rating for MRK stock is currently 1.90, trading closer to a bullish pattern in the stock market.
Guru’s Opinion on Merck & Co. Inc. [MRK]:
Based on careful and fact-backed analyses by Wall Street experts, the current consensus on the target price for MRK shares is $96.33 per share. Analysis on target price and performance of stocks is usually carefully studied by market experts, and the current Wall Street consensus on MRK stock is a recommendation set at 1.90. This rating represents a strong Buy recommendation, on the scale from 1 to 5, where 5 would mean strong sell, 4 represents Sell, 3 is Hold, and 2 indicates Buy.
Bernstein have made an estimate for Merck & Co. Inc. shares, keeping their opinion on the stock as Outperform, with their previous recommendation back on November 10, 2020. While these analysts kept the previous recommendation, Berenberg raised their target price to Hold. The new note on the price target was released on September 29, 2020, representing the official price target for Merck & Co. Inc. stock. Previously, the target price had yet another raise from $91 to $105, while Goldman kept a Buy rating on MRK stock.
The Average True Range (ATR) for Merck & Co. Inc. is set at 1.39, with the Price to Sales ratio for MRK stock in the period of the last 12 months amounting to 3.86. The Price to Book ratio for the last quarter was 7.41, with the Price to Cash per share for the same quarter was set at 3.23.
MRK Stock Performance Analysis:
Merck & Co. Inc. [MRK] gain into the green zone at the end of the last week, gaining into a positive trend and gaining by 1.77. With this latest performance, MRK shares dropped by -2.19% in over the last four-week period, additionally sinking by -13.02% over the last 6 months – not to mention a drop of -6.10% in the past year of trading.
Overbought and oversold stocks can be easily traced with the Relative Strength Index (RSI), where an RSI result of over 70 would be overbought, and any rate below 30 would indicate oversold conditions. An RSI rate of 50 would represent a neutral market momentum. The current RSI for MRK stock in for the last two-week period is set at 44.44, with the RSI for the last a single of trading hit 49.60, and the three-weeks RSI is set at 42.57 for Merck & Co. Inc. [MRK]. The present Moving Average for the last 50 days of trading for this stock 77.90, while it was recorded at 73.38 for the last single week of trading, and 79.94 for the last 200 days.
Insight into Merck & Co. Inc. Fundamentals:
Operating Margin for any stock indicates how profitable investing would be, and Merck & Co. Inc. [MRK] shares currently have an operating margin of +26.16 and a Gross Margin at +73.77. Merck & Co. Inc.’s Net Margin is presently recorded at +14.72.
Return on Total Capital for MRK is now 22.39, given the latest momentum, and Return on Invested Capital for the company is 13.93. Return on Equity for this stock inclined to 27.59, with Return on Assets sitting at 8.03. When it comes to the capital structure of this company, Merck & Co. Inc. [MRK] has a Total Debt to Total Equity ratio set at 132.14. Additionally, MRK Total Debt to Total Capital is recorded at 56.92, with Total Debt to Total Assets ending up at 36.53. Long-Term Debt to Equity for the company is recorded at 105.55, with the Long-Term Debt to Total Capital now at 45.47.
Reflecting on the efficiency of the workforce at the company, Merck & Co. Inc. [MRK] managed to generate an average of $95,500 per employee. Receivables Turnover for the company is 6.56 with a Total Asset Turnover recorded at a value of 0.55.Merck & Co. Inc.’s liquidity data is similarly interesting compelling, with a Quick Ratio of 0.80 and a Current Ratio set at 1.00.
MRK Stock EPS
With the latest financial reports released by the company, Merck & Co. Inc. posted 1.5/share EPS, while the average EPS was predicted by analysts to be reported at 1.34/share. When compared, the two values demonstrate that the company surpassed the estimates by a Surprise Factor of 11.90%. The progress of the company may be observed through the prism of EPS growth rate, while Wall Street analysts are focusing on predicting the 5-year EPS growth rate for MRK. When it comes to the mentioned value, analysts are expecting to see the 5-year EPS growth rate for Merck & Co. Inc. go to 9.00%.
Merck & Co. Inc. [MRK] Insider Position Details
There are presently around $138,931 million, or 75.70% of MRK stock, in the hands of institutional investors. The top three institutional holders of MRK stocks are: VANGUARD GROUP INC with ownership of 208,410,644, which is approximately -0.693% of the company’s market cap and around 0.10% of the total institutional ownership; BLACKROCK INC., holding 195,017,904 shares of the stock with an approximate value of $14.46 billion in MRK stocks shares; and STATE STREET CORP, currently with $8.46 billion in MRK stock with ownership of nearly -2.459% of the company’s market capitalization.
Positions in Merck & Co. Inc. stocks held by institutional investors increased at the end of February and at the time of the February reporting period, where 1,507 institutional holders increased their position in Merck & Co. Inc. [NYSE:MRK] by around 80,644,795 shares. Additionally, 1,032 investors decreased positions by around 90,001,934 shares, while 284 investors held positions by with 1,702,502,619 shares. The mentioned changes placed institutional holdings at 1,873,149,348 shares, according to the latest SEC report filing. MRK stock had 269 new institutional investments in for a total of 7,813,147 shares, while 119 institutional investors sold positions of 5,705,386 shares during the same period.